Correct answer:

Crohn’s disease is a non-specific inflammatory disease of the alimentary canal, with diseased segments sandwiched between normal segments (i.e. it is discontinuous). Crohn first described its occurrence in the ileum and termed it ‘regional ileitis’. However, this description is inaccurate, as the disease may affect any part of the alimentary tract from mouth to anus. Crohn’s disease may affect the large bowel alone.